Chemicals and Drugs

APOBEC Deaminases

A family of conserved cytidine deaminases that catalyze the DEAMINATION of CYTIDINE to URIDINE. They are characterized by N and C-terminal zinc-dependent catalytic domains and have important functions in RNA EDITING; EPIGENTIC PROCESSES; and the INNATE IMMUNE RESPONSE against viruses.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of conserved cytidine deaminases that catalyze the DEAMINATION of CYTIDINE to URIDINE. They are characterized by N and C-terminal zinc-dependent catalytic domains and have important functions in RNA EDITING; EPIGENTIC PROCESSES; and the INNATE IMMUNE RESPONSE against viruses.

MeSH Record

Classification

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MeSH Record

Synonyms

7 entry terms
  • AID-APOBEC Deaminases
  • APOBEC Enzymes
  • APOBEC Family Proteins
  • Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptides
  • AID APOBEC Deaminases
  • Deaminases, AID-APOBEC
  • Deaminases, APOBEC

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017

MeSH Record

Previous Indexing

  • Cytidine Deaminase (1991-2016)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. APOBEC Deaminases. Medical Subject Headings (MeSH). 2026. Unique ID D000071478. http://id.nlm.nih.gov/mesh/2026/D000071478
  2. APOBEC Deaminases. In: Wikipedia. https://en.wikipedia.org/wiki/APOBEC
  3. APOBEC Deaminases. In: Wikidata. https://www.wikidata.org/wiki/Q4653351