Chemicals and Drugs

APOBEC-1 Deaminase

An APOBEC deaminase catalytic subunit of the apolipoprotein B (APOB) MESSENGER RNA (mRNA) editing enzyme complex that is involved in post-transcriptional editing of a CAA codon for GLYCINE to a UAA STOP CODON in the ApoB mRNA. It also functions in CGA (ARGININE) to UGA STOP CODON editing of NEUROFIBROMIN 1 mRNA and EPIGENETIC PROCESSES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An APOBEC deaminase catalytic subunit of the apolipoprotein B (APOB) MESSENGER RNA (mRNA) editing enzyme complex that is involved in post-transcriptional editing of a CAA codon for GLYCINE to a UAA STOP CODON in the ApoB mRNA. It also functions in CGA (ARGININE) to UGA STOP CODON editing of NEUROFIBROMIN 1 mRNA and EPIGENETIC PROCESSES.

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Classification

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Synonyms

13 entry terms
  • APOBEC-1
  • APOBEC-1 Protein
  • APOBEC1 Deaminase
  • APOBEC1 Protein
  • ApoB mRNA Editing Catalytic Subunit
  • Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide 1
  • HEPR Protein
  • APOBEC 1 Deaminase
  • APOBEC 1 Protein
  • Deaminase, APOBEC-1
  • Deaminase, APOBEC1
  • Apo B mRNA Editing Protein
  • Apolipoprotein B mRNA Editing Enzyme

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017; use APOLIPOPROTEIN B MRNA EDITING ENZYME 1991-2016

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References

  1. National Library of Medicine. APOBEC-1 Deaminase. Medical Subject Headings (MeSH). 2026. Unique ID D000071479. http://id.nlm.nih.gov/mesh/2026/D000071479
  2. APOBEC-1 Deaminase. In: Wikidata. https://www.wikidata.org/wiki/Q21104791