Structured Summary
Abstract
Retrovirus-associated DNA sequences (v-sis) originally isolated from the simian sarcoma virus (SSV). The proto-oncogene c-sis codes for a growth factor which is the B chain of PLATELET-DERIVED GROWTH FACTOR. v-sis or overexpression of c-sis causes tumorigenesis. The human sis gene is located at 22q12.3-13.1 on the long arm of chromosome 22.
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Synonyms
31 entry terms
- Genes, sis
- Gene, sis
- sis Gene
- Genes, PDGFB
- c-sis Genes
- c-sis Proto-Oncogenes
- sis Oncogene
- v-sis Genes
- v-sis Oncogenes
- Gene, PDGFB
- Gene, c-sis
- Gene, v-sis
- Genes, c-sis
- Genes, v-sis
- Oncogene, sis
- Oncogene, v-sis
- Oncogenes, sis
- Oncogenes, v-sis
- PDGFB Gene
- PDGFB Genes
- Proto-Oncogene, c-sis
- Proto-Oncogenes, c-sis
- c sis Genes
- c sis Proto Oncogenes
- c-sis Gene
- c-sis Proto-Oncogene
- sis Oncogenes
- v sis Genes
- v sis Oncogenes
- v-sis Gene
- v-sis Oncogene
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Aspects Covered
6 allowable subheadings
Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.
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History Note
2000; use ONCOGENES 1988-1999
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Previous Indexing
- Oncogenes (1983-1999)
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References
- National Library of Medicine. sis Genes. Medical Subject Headings (MeSH). 2026. Unique ID D020571. http://id.nlm.nih.gov/mesh/2026/D020571
- sis Genes. In: Wikipedia. https://en.wikipedia.org/wiki/PDGFB
- sis Genes. In: Wikidata. https://www.wikidata.org/wiki/Q18030421