Chemicals and Drugs

p38 Mitogen-Activated Protein Kinases

A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes including CELL GROWTH PROCESSES; CELL DIFFERENTIATION; APOPTOSIS; and cellular responses to INFLAMMATION. The P38 MAP kinases are regulated by CYTOKINE RECEPTORS and can be activated in response to bacterial pathogens.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes including CELL GROWTH PROCESSES; CELL DIFFERENTIATION; APOPTOSIS; and cellular responses to INFLAMMATION. The P38 MAP kinases are regulated by CYTOKINE RECEPTORS and can be activated in response to bacterial pathogens.

MeSH Record

Classification

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MeSH Record

Synonyms

12 entry terms
  • Mitogen-Activated Protein Kinase p38
  • p38 MAP Kinase
  • p38 MAPK
  • p38 Mitogen-Activated Protein Kinase
  • p38 Protein Kinase
  • p38 SAPK
  • MAP Kinase, p38
  • MAPK, p38
  • Mitogen Activated Protein Kinase p38
  • Protein Kinase, p38
  • p38 Mitogen Activated Protein Kinase
  • p38 Mitogen Activated Protein Kinases

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2005(1994)

MeSH Record

Previous Indexing

  • Ca(2+)-Calmodulin Dependent Protein Kinase (1994-2000)
  • Mitogen-Activated Protein Kinases (2000-2004)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. p38 Mitogen-Activated Protein Kinases. Medical Subject Headings (MeSH). 2026. Unique ID D048051. http://id.nlm.nih.gov/mesh/2026/D048051
  2. p38 Mitogen-Activated Protein Kinases. In: Wikipedia. https://en.wikipedia.org/wiki/P38_mitogen-activated_protein_kinases
  3. p38 Mitogen-Activated Protein Kinases. In: Wikidata. https://www.wikidata.org/wiki/Q2043632