Structured Summary
Abstract
A 38-kDa mitogen-activated protein kinase that is abundantly expressed in a broad variety of cell types. It is involved in the regulation of cellular stress responses as well as the control of proliferation and survival of many cell types. The kinase activity of the enzyme is inhibited by the pyridinyl-imidazole compound SB 203580.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
21 entry terms
- CSAID-Binding Protein
- Cytokine Suppressive Anti-inflammatory Drug Binding Protein
- Kinase CSBP
- MAPK14
- MAPK14 Mitogen-Activated Protein Kinase
- MAX-Interacting Protein 2
- Mxi2 Protein
- SAPK2a
- Stress-activated protein kinase 2a
- p38alpha MAP Kinase
- p38alpha Mitogen-Activated Protein Kinase
- p38alphaMAPK
- CSAID Binding Protein
- CSBP, Kinase
- Cytokine Suppressive Anti inflammatory Drug Binding Protein
- MAP Kinase, p38alpha
- MAPK14 Mitogen Activated Protein Kinase
- MAX Interacting Protein 2
- Mitogen Activated Protein Kinase 14
- Stress activated protein kinase 2a
- p38alpha Mitogen Activated Protein Kinase
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2005(1994)
MeSH Record
Previous Indexing
- Ca(2+)-Calmodulin Dependent Protein Kinase (1995-1999)
- Mitogen-Activated Protein Kinases (2000-2004)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Mitogen-Activated Protein Kinase 14. Medical Subject Headings (MeSH). 2026. Unique ID D048308. http://id.nlm.nih.gov/mesh/2026/D048308
- Mitogen-Activated Protein Kinase 14. In: Wikidata. https://www.wikidata.org/wiki/Q6714402