Structured Summary
Abstract
Retrovirus-associated DNA sequences (v-myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto-oncogene c-myb codes for a nuclear protein involved in transcriptional regulation and appears to be essential for hematopoietic cell proliferation. The human myb gene is located at 6q22-23 on the short arm of chromosome 6. This is the point of break in translocations involved in T-cell acute lymphatic leukemia and in some ovarian cancers and melanomas. (From Ibelgaufts, Dictionary of Cytokines, 1995).
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Synonyms
27 entry terms
- Genes, myb
- Gene, myb
- myb Gene
- c-myb Genes
- c-myb Proto-Oncogenes
- myb Oncogene
- v-myb Genes
- v-myb Oncogenes
- Gene, c-myb
- Gene, v-myb
- Genes, c-myb
- Genes, v-myb
- Oncogene, myb
- Oncogene, v-myb
- Oncogenes, myb
- Oncogenes, v-myb
- Proto-Oncogene, c-myb
- Proto-Oncogenes, c-myb
- c myb Genes
- c myb Proto Oncogenes
- c-myb Gene
- c-myb Proto-Oncogene
- myb Oncogenes
- v myb Genes
- v myb Oncogenes
- v-myb Gene
- v-myb Oncogene
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Aspects Covered
6 allowable subheadings
Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.
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History Note
2000; use ONCOGENES 1985-1999
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Previous Indexing
- Genes, Viral (1983-1999)
- Oncogenes (1983-1999)
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References
- National Library of Medicine. myb Genes. Medical Subject Headings (MeSH). 2026. Unique ID D020570. http://id.nlm.nih.gov/mesh/2026/D020570
- myb Genes. In: Wikipedia. https://en.wikipedia.org/wiki/MYB_(gene)
- myb Genes. In: Wikidata. https://www.wikidata.org/wiki/Q18029694