Structured Summary
Abstract
Retrovirus-associated DNA sequences (fos) originally isolated from the Finkel-Biskis-Jinkins (FBJ-MSV) and Finkel-Biskis-Reilly (FBR-MSV) murine sarcoma viruses. The proto-oncogene protein c-fos codes for a nuclear protein which is involved in growth-related transcriptional control. The insertion of c-fos into FBJ-MSV or FBR-MSV induces osteogenic sarcomas in mice. The human c-fos gene is located at 14q21-31 on the long arm of chromosome 14.
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Synonyms
14 entry terms
- Genes, fos
- fos Gene
- c-fos Genes
- c-fos Proto-Oncogenes
- v-fos Genes
- v-fos Oncogenes
- c fos Genes
- c fos Proto Oncogenes
- c-fos Gene
- c-fos Proto-Oncogene
- v fos Genes
- v fos Oncogenes
- v-fos Gene
- v-fos Oncogene
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Aspects Covered
6 allowable subheadings
Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.
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Indexing Annotation
fos stands for "Finkel" & "Osteogenic Sarcoma"
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History Note
92
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Previous Indexing
- Oncogenes (1983-1991)
- Proto-Oncogenes (1985-1991)
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References
- National Library of Medicine. fos Genes. Medical Subject Headings (MeSH). 2026. Unique ID D016762. http://id.nlm.nih.gov/mesh/2026/D016762
- fos Genes. In: Wikidata. https://www.wikidata.org/wiki/Q14906123