Diseases

beta-Mannosidosis

An inborn error of metabolism marked by a defect in the lysosomal isoform of BETA-MANNOSIDASE that results in lysosomal accumulation of mannose-rich intermediate metabolites containing 1,4-beta linkages. The human disease occurs through autosomal recessive inheritance and manifests in the form of a variety of symptoms that depend upon the type of gene mutation.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An inborn error of metabolism marked by a defect in the lysosomal isoform of BETA-MANNOSIDASE that results in lysosomal accumulation of mannose-rich intermediate metabolites containing 1,4-beta linkages. The human disease occurs through autosomal recessive inheritance and manifests in the form of a variety of symptoms that depend upon the type of gene mutation.

MeSH Record

Classification

Broader headings

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MeSH Record

See Also

MeSH Record

Synonyms

10 entry terms
  • Lysosomal beta A Mannosidosis
  • Lysosomal beta-Mannosidase Deficiency
  • Mannosidosis, beta A, Lysosomal
  • beta-Mannosidase Deficiency
  • Lysosomal beta Mannosidase Deficiency
  • Lysosomal beta-Mannosidase Deficiencies
  • beta Mannosidase Deficiency
  • beta Mannosidosis
  • beta-Mannosidase Deficiencies
  • beta-Mannosidoses

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2004

MeSH Record

Previous Indexing

  • Mannosidase Deficiency Diseases (1984-2003)

MeSH Hierarchy

Tree Numbers

  1. C16w.320w.565w.202w.607w.750w
  2. C16w.320w.565w.595w.577w.750w
  3. C18.452w.648w.202w.607w.750w
  4. C18.452w.648w.595w.577w.750w

AMA Style

References

  1. National Library of Medicine. beta-Mannosidosis. Medical Subject Headings (MeSH). 2026. Unique ID D044905. http://id.nlm.nih.gov/mesh/2026/D044905
  2. beta-Mannosidosis. In: Wikipedia. https://en.wikipedia.org/wiki/Beta-mannosidosis
  3. beta-Mannosidosis. In: Wikidata. https://www.wikidata.org/wiki/Q291617