Structured Summary
Abstract
An enzyme that catalyzes the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides. The enzyme plays a role in the lysosomal degradation of the N-glycosylprotein glycans. Defects in the lysosomal form of the enzyme in humans result in a buildup of mannoside intermediate metabolites and the disease BETA-MANNOSIDOSIS.
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Broader headings
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Synonyms
6 entry terms
- beta-D-Mannosidase
- beta-Mannanase
- manA protein (beta-Mannosidase)
- beta D Mannosidase
- beta Mannanase
- beta Mannosidase
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
/defic: consider also BETA-MANNOSIDOSIS
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History Note
2004; use BETA-MANNOSIDASE (NM) 1980-2003
MeSH Record
Previous Indexing
- Mannosidases (1980-2003)
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AMA Style
References
- National Library of Medicine. beta-Mannosidase. Medical Subject Headings (MeSH). 2026. Unique ID D044902. http://id.nlm.nih.gov/mesh/2026/D044902
- beta-Mannosidase. In: Wikidata. https://www.wikidata.org/wiki/Q21173172