Structured Summary
Abstract
Retrovirus-associated DNA sequences (abl) originally isolated from the Abelson murine leukemia virus (Ab-MuLV). The proto-oncogene abl (c-abl) codes for a protein that is a member of the tyrosine kinase family. The human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It is activated by translocation to bcr on chromosome 22 in chronic myelogenous leukemia.
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Synonyms
37 entry terms
- Genes, abl
- Gene, abl
- abl Gene
- abl Oncogene
- bcr-abl Proto-Oncogenes
- bcr-v-abl Oncogenes
- c-abl Genes
- c-abl Proto-Oncogenes
- v-abl Genes
- v-abl Oncogenes
- Gene, c-abl
- Gene, v-abl
- Genes, c-abl
- Genes, v-abl
- Oncogene, abl
- Oncogene, bcr-v-abl
- Oncogene, v-abl
- Oncogenes, abl
- Oncogenes, bcr-v-abl
- Oncogenes, v-abl
- Proto-Oncogene, bcr-abl
- Proto-Oncogene, c-abl
- Proto-Oncogenes, bcr-abl
- Proto-Oncogenes, c-abl
- abl Oncogenes
- bcr abl Proto Oncogenes
- bcr v abl Oncogenes
- bcr-abl Proto-Oncogene
- bcr-v-abl Oncogene
- c abl Genes
- c abl Proto Oncogenes
- c-abl Gene
- c-abl Proto-Oncogene
- v abl Genes
- v abl Oncogenes
- v-abl Gene
- v-abl Oncogene
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Aspects Covered
6 allowable subheadings
Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.
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Indexing Annotation
abl stands for "ABelson Leukemia"
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History Note
91
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Previous Indexing
- Oncogenes (1982-1990)
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References
- National Library of Medicine. abl Genes. Medical Subject Headings (MeSH). 2026. Unique ID D016313. http://id.nlm.nih.gov/mesh/2026/D016313
- abl Genes. In: Wikipedia. https://en.wikipedia.org/wiki/Tyrosine-protein_kinase_ABL1
- abl Genes. In: Wikidata. https://www.wikidata.org/wiki/Q587961