Chemicals and Drugs

Vilazodone Hydrochloride

A benzofuran, indole, and piperazine derivative that functions as a SEROTONIN UPTAKE INHIBITOR and partial SEROTONIN 5-HT1 RECEPTOR AGONIST. It is used as an ANTIDEPRESSIVE AGENT.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A benzofuran, indole, and piperazine derivative that functions as a SEROTONIN UPTAKE INHIBITOR and partial SEROTONIN 5-HT1 RECEPTOR AGONIST. It is used as an ANTIDEPRESSIVE AGENT.

Chemical Identity

Chemical Information

Molecular Formula
C26H28ClN5O2
Molecular Weight
478.0 g/mol
CAS Registry No.
163521-08-2
IUPAC Name
5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl]-1-benzofuran-2-carboxamide;hydrochloride
InChIKey
RPZBRGFNBNQSOP-UHFFFAOYSA-N
SMILES
C1CN(CCN1CCCCC2=CNC3=C2C=C(C=C3)C#N)C4=CC5=C(C=C4)OC(=C5)C(=O)N.Cl
MeSH Unique ID
D000069503
Source
PubChem CID 6918313

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

12 entry terms
  • 2-benzofurancarboxamide, 5-(4-(4-(5-cyano-1H-indol-3-yl)butyl)-1-piperazinyl)-, hydrochloride (1:1)
  • Vilazodone HCl
  • HCl, Vilazodone
  • Hydrochloride, Vilazodone
  • 5-(4-(4-(5-cyano-3-indolyl)butyl)-1-piperazinyl)benzofuran-2-carboxamide
  • EMB-68843
  • EMD 68843
  • Viibryd
  • Vilazodone
  • 68843, EMD
  • EMB 68843
  • EMB68843

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2016 (2004)

MeSH Hierarchy

Tree Numbers

  1. D03w.383.606w.980
  2. D03w.633.100.127w.818
  3. D03w.633.100.473.957

AMA Style

References

  1. National Library of Medicine. Vilazodone Hydrochloride. Medical Subject Headings (MeSH). 2026. Unique ID D000069503. http://id.nlm.nih.gov/mesh/2026/D000069503
  2. Vilazodone Hydrochloride. In: Wikidata. https://www.wikidata.org/wiki/Q27139037
  3. Vilazodone Hydrochloride. In: PubChem Compound. CID 6918313. https://pubchem.ncbi.nlm.nih.gov/compound/6918313