Chemicals and Drugs

Antidepressive Agents

Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.

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Synonyms

13 entry terms
  • Antidepressant
  • Antidepressant Drug
  • Antidepressant Drugs
  • Antidepressant Medication
  • Antidepressants
  • Antidepressive Agent
  • Agent, Antidepressive
  • Drug, Antidepressant
  • Medication, Antidepressant
  • Thymoanaleptic
  • Thymoanaleptics
  • Thymoleptic
  • Thymoleptics

MeSH Record

Aspects Covered

22 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

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Indexing Annotation

general or unspecified; prefer specific groups

MeSH Record

History Note

66; PSYCHIC ENERGIZERS was see ANTIDEPRESSIVE AGENTS 1963-94; THYMOLEPTICS was see TRANQUILIZING AGENTS 1969-78

MeSH Hierarchy

Tree Number

  1. D27.505.954.427.700.122w

MeSH Record

NLM Classification

QV 77.5

AMA Style

References

  1. National Library of Medicine. Antidepressive Agents. Medical Subject Headings (MeSH). 2026. Unique ID D000928. http://id.nlm.nih.gov/mesh/2026/D000928
  2. Antidepressive Agents. In: Wikipedia. https://en.wikipedia.org/wiki/Antidepressant
  3. Antidepressive Agents. In: Wikidata. https://www.wikidata.org/wiki/Q76560