Chemicals and Drugs

Vecuronium Bromide

Monoquaternary homolog of PANCURONIUM. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other established neuromuscular blocking agents.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Monoquaternary homolog of PANCURONIUM. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other established neuromuscular blocking agents.

Chemical Identity

Chemical Information

Molecular Formula
C34H57BrN2O4
Molecular Weight
637.7 g/mol
CAS Registry No.
50700-72-6
IUPAC Name
[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetyloxy-10,13-dimethyl-16-(1-methylpiperidin-1-ium-1-yl)-2-piperidin-1-yl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate bromide
InChIKey
VEPSYABRBFXYIB-PWXDFCLTSA-M
SMILES
CC(=O)O[C@H]1C[C@@H]2CC[C@@H]3[C@@H]([C@]2(C[C@@H]1N4CCCCC4)C)CC[C@]5([C@H]3C[C@@H]([C@@H]5OC(=O)C)[N+]6(CCCCC6)C)C.[Br-]
MeSH Unique ID
D014673
Source
PubChem CID 39764

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

24 entry terms
  • Vecuronium Hydrobromide
  • Bromide, Vecuronium
  • Hydrobromide, Vecuronium
  • NC-45
  • Norcuron
  • ORG-NC 45
  • ORG-NC-45
  • ORG-NC45
  • Vecuronium
  • Vecuronium Bromide, Quaternary Ion
  • Vecuronium Citrate
  • Vecuronium Hydrochloride
  • Vecuronium Maleate
  • Vecuronium Phosphate
  • Citrate, Vecuronium
  • Hydrochloride, Vecuronium
  • Maleate, Vecuronium
  • NC 45
  • NC45
  • ORG NC 45
  • ORG NC45
  • ORGNC 45
  • ORGNC45
  • Phosphate, Vecuronium

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

95; was VECURONIUM 1987-94; VECURONIUM BROMIDE was see VECURONIUM 1987-94

MeSH Record

Previous Indexing

  • Androstanes (1968-1971)
  • Pancuronium/analogs & derivatives (1972-1986)

MeSH Hierarchy

Tree Number

  1. D04w.210.500w.054.040w.920w

MeSH Record

NLM Classification

QV 140

AMA Style

References

  1. National Library of Medicine. Vecuronium Bromide. Medical Subject Headings (MeSH). 2026. Unique ID D014673. http://id.nlm.nih.gov/mesh/2026/D014673
  2. Vecuronium Bromide. In: Wikipedia. https://en.wikipedia.org/wiki/Vecuronium_bromide
  3. Vecuronium Bromide. In: Wikidata. https://www.wikidata.org/wiki/Q27108523
  4. Vecuronium Bromide. In: PubChem Compound. CID 39764. https://pubchem.ncbi.nlm.nih.gov/compound/39764