Chemicals and Drugs

Vascular Endothelial Growth Factor Receptors

A family of closely related RECEPTOR PROTEIN-TYROSINE KINASES that bind vascular endothelial growth factors. They share a cluster of seven extracellular IG-LIKE DOMAINS which are important for ligand binding. They are highly expressed in vascular endothelial cells and are critical for the physiological and pathological growth, development and maintenance of blood and lymphatic vessels.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of closely related RECEPTOR PROTEIN-TYROSINE KINASES that bind vascular endothelial growth factors. They share a cluster of seven extracellular IG-LIKE DOMAINS which are important for ligand binding. They are highly expressed in vascular endothelial cells and are critical for the physiological and pathological growth, development and maintenance of blood and lymphatic vessels.

MeSH Record

Classification

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Synonyms

12 entry terms
  • Receptor, Vascular Endothelial Cell Growth Factor
  • Receptor, Vascular Permeability Factor
  • Receptors, Vascular Endothelial Growth Factor
  • VEGF Receptor
  • VEGF Receptors
  • VPF Receptor
  • Vascular Endothelial Cell Growth Factor Receptor
  • Vascular Endothelial Growth Factor Receptor
  • Vascular Permeability Factor Receptor
  • Receptors, VEGF
  • Endothelial Growth Factor Receptor
  • Receptor, Endothelial Growth Factors

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

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Indexing Annotation

general; prefer specifics

MeSH Record

History Note

2003; use RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR (NM) 1991-2002; for ENDOTHELIAL GROWTH FACTOR RECEPTOR use RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR (NM) 1985-2003

MeSH Record

Previous Indexing

  • Protein-Tyrosine Kinase (1993)
  • Receptor Protein-Tyrosine Kinases (1994-2002)
  • Receptors, Growth Factor (1993-2002)
  • Receptors, Mitogen (1991-1992)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.913w.696w.620.682w.725w.400w.950w
  2. D12.776w.476.568w.400w.950w
  3. D12.776w.543w.750w.630w.750w
  4. D12.776w.543w.750w.750w.400w.910w

AMA Style

References

  1. National Library of Medicine. Vascular Endothelial Growth Factor Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D040262. http://id.nlm.nih.gov/mesh/2026/D040262
  2. Vascular Endothelial Growth Factor Receptors. In: Wikipedia. https://en.wikipedia.org/wiki/VEGF_receptor
  3. Vascular Endothelial Growth Factor Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q4356503