Chemicals and Drugs

Uracil Mustard

Nitrogen mustard derivative of URACIL. It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Nitrogen mustard derivative of URACIL. It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage.

Chemical Identity

Chemical Information

Molecular Formula
C8H11Cl2N3O2
Molecular Weight
252.09 g/mol
CAS Registry No.
66-75-1
IUPAC Name
5-[bis(2-chloroethyl)amino]-1H-pyrimidine-2,4-dione
InChIKey
IDPUKCWIGUEADI-UHFFFAOYSA-N
SMILES
C1=C(C(=O)NC(=O)N1)N(CCCl)CCCl
MeSH Unique ID
D014499
Source
PubChem CID 6194

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

3 entry terms
  • 5-(Bis(2-chloroethyl)amino)-2,4-(1H,3H)pyrimidinedione
  • Uramustine
  • Mustard, Uracil

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

66(63)

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.526.728w.650w.913w
  2. D03w.383.742.698.875w.949w

AMA Style

References

  1. National Library of Medicine. Uracil Mustard. Medical Subject Headings (MeSH). 2026. Unique ID D014499. http://id.nlm.nih.gov/mesh/2026/D014499
  2. Uracil Mustard. In: Wikipedia. https://en.wikipedia.org/wiki/Uramustine
  3. Uracil Mustard. In: Wikidata. https://www.wikidata.org/wiki/Q15211075
  4. Uracil Mustard. In: PubChem Compound. CID 6194. https://pubchem.ncbi.nlm.nih.gov/compound/6194