Chemicals and Drugs

Mustard Compounds

Strong alkylating and immunosuppressive agents whose biological activity is based on the presence of bis(2-chloroethyl)- groups. Although otherwise structurally diverse, the compounds have in common the capacity to contribute alkyl groups to DNA. They are generally highly toxic but include among their number many widely used and effective antineoplastic agents.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Strong alkylating and immunosuppressive agents whose biological activity is based on the presence of bis(2-chloroethyl)- groups. Although otherwise structurally diverse, the compounds have in common the capacity to contribute alkyl groups to DNA. They are generally highly toxic but include among their number many widely used and effective antineoplastic agents.

MeSH Record

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MeSH Record

Synonyms

1 entry terms
  • Compounds, Mustard

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

68

MeSH Hierarchy

Tree Number

  1. D02w.455w.526.728w

AMA Style

References

  1. National Library of Medicine. Mustard Compounds. Medical Subject Headings (MeSH). 2026. Unique ID D009150. http://id.nlm.nih.gov/mesh/2026/D009150
  2. Mustard Compounds. In: Wikipedia. https://en.wikipedia.org/wiki/Mustard_compounds
  3. Mustard Compounds. In: Wikidata. https://www.wikidata.org/wiki/Q16818137