Chemicals and Drugs

Tryptophan Hydroxylase

An enzyme that catalyzes the hydroxylation of TRYPTOPHAN to 5-HYDROXYTRYPTOPHAN in the presence of NADPH and molecular oxygen. It is important in the biosynthesis of SEROTONIN.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that catalyzes the hydroxylation of TRYPTOPHAN to 5-HYDROXYTRYPTOPHAN in the presence of NADPH and molecular oxygen. It is important in the biosynthesis of SEROTONIN.

MeSH Record

Classification

Broader headings

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See Also

MeSH Record

Synonyms

3 entry terms
  • Tryptophan Monooxygenase
  • Hydroxylase, Tryptophan
  • Monooxygenase, Tryptophan

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

78(73); was see under HYDROXYLASES 1975-77

MeSH Record

Previous Indexing

  • Hydroxylases (1966-1972)

MeSH Hierarchy

Tree Number

  1. D08.811w.682w.690w.708.870w

AMA Style

References

  1. National Library of Medicine. Tryptophan Hydroxylase. Medical Subject Headings (MeSH). 2026. Unique ID D014365. http://id.nlm.nih.gov/mesh/2026/D014365
  2. Tryptophan Hydroxylase. In: Wikipedia. https://en.wikipedia.org/wiki/Tryptophan_hydroxylase
  3. Tryptophan Hydroxylase. In: Wikidata. https://www.wikidata.org/wiki/Q418293