Structured Summary
Abstract
Plant-derived ribosome-inactivating protein (RIP) purified from the Chinese medicinal herb tian-hua-fen which is obtained from the root tubers of Trichosanthes kirilowii. It has been used as an abortifacient and in the treatment of trophoblastic tumors. GLQ223 (Compound Q), a highly purified form of trichosanthin, has been proposed as antiviral treatment for AIDS.
MeSH Record
Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
8 entry terms
- Compound Q
- alpha-Trichosanthin
- alpha Trichosanthin
- GLQ-223
- GLQ223
- T'ien-hua-fen
- Tian-hua-fen
- GLQ 223
MeSH Record
Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
/drug eff /ultrastruct permitted
MeSH Record
History Note
90
MeSH Record
Previous Indexing
- Abortifacient Agents, Non-Steroidal (1977-1989)
- Plant Proteins (1976-1989)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Trichosanthin. Medical Subject Headings (MeSH). 2026. Unique ID D015978. http://id.nlm.nih.gov/mesh/2026/D015978
- Trichosanthin. In: Wikipedia. https://en.wikipedia.org/wiki/Trichosanthin
- Trichosanthin. In: Wikidata. https://www.wikidata.org/wiki/Q7840974