Phenomena and Processes

Translesion DNA Synthesis

DNA damage tolerant, error-prone DNA replication by specialized DNA POLYMERASES that can accommodate damaged bases in their active sites and insert NUCLEOTIDES in the strand directly opposite the DNA DAMAGE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

DNA damage tolerant, error-prone DNA replication by specialized DNA POLYMERASES that can accommodate damaged bases in their active sites and insert NUCLEOTIDES in the strand directly opposite the DNA DAMAGE.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

27 entry terms
  • Trans-Lesion DNA Replication
  • Trans-Lesion DNA Synthesis
  • Trans-Lesion Synthesis
  • Trans-Lesional DNA Replication
  • Trans-Lesional DNA Synthesis
  • Translesion DNA Replication
  • Translesion Synthesis
  • Translesion Synthesis Pathway
  • Translesional DNA Synthesis
  • Translesional Synthesis
  • Translesional Synthesis Pathway
  • DNA Replication, Trans-Lesion
  • DNA Replication, Trans-Lesional
  • DNA Replication, Translesion
  • DNA Syntheses, Trans-Lesion
  • DNA Synthesis, Trans-Lesion
  • DNA Synthesis, Trans-Lesional
  • DNA Synthesis, Translesion
  • DNA Synthesis, Translesional
  • Replication, Translesion DNA
  • Replications, Trans-Lesional DNA
  • Replications, Translesion DNA
  • Syntheses, Translesional DNA
  • Trans Lesion DNA Replication
  • Trans Lesion DNA Synthesis
  • Trans Lesion Synthesis
  • Trans Lesional DNA Replication

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2024

MeSH Record

Previous Indexing

  • DNA Replication (1985-2023)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Translesion DNA Synthesis. Medical Subject Headings (MeSH). 2026. Unique ID D000096963. http://id.nlm.nih.gov/mesh/2026/D000096963
  2. Translesion DNA Synthesis. In: Wikidata. https://www.wikidata.org/wiki/Q14902248