Structured Summary
Abstract
A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a N-glycosylated protein, molecular weight 28 kD, produced by a vast range of cell types and found in a variety of tissues and body fluids. It has been shown to suppress metastasis and inhibit tumor invasion in vitro.
MeSH Record
Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
3 entry terms
- TIMP-1
- Metalloproteinase-1 Tissue Inhibitor
- Tissue Inhibitor of Metalloproteinase 1
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
98; see TISSUE-INHIBITOR OF METALLOPROTEINASE-1 (NM) 1980-97
MeSH Record
Previous Indexing
- Glycoproteins (1990-1997)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Tissue Inhibitor of Metalloproteinase-1. Medical Subject Headings (MeSH). 2026. Unique ID D019715. http://id.nlm.nih.gov/mesh/2026/D019715
- Tissue Inhibitor of Metalloproteinase-1. In: Wikidata. https://www.wikidata.org/wiki/Q24777113