Structured Summary
Abstract
Beta-lactam antibiotics that differ from PENICILLINS in having the thiazolidine sulfur atom replaced by carbon, the sulfur then becoming the first atom in the side chain. They are unstable chemically, but have a very broad antibacterial spectrum. Thienamycin and its more stable derivatives are proposed for use in combinations with enzyme inhibitors.
MeSH Record
Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
2 entry terms
- Antibiotics, Thienamycin
- Thienamycin Antibiotics
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
83
MeSH Record
Previous Indexing
- Amides (1966-1973)
- Antibiotics (1966-1982)
- Lactams (1974-1982)
MeSH Hierarchy
Tree Numbers
MeSH Record
NLM Classification
QV 350
AMA Style
References
- National Library of Medicine. Thienamycins. Medical Subject Headings (MeSH). 2026. Unique ID D013845. http://id.nlm.nih.gov/mesh/2026/D013845
- Thienamycins. In: Wikidata. https://www.wikidata.org/wiki/Q76850318