Structured Summary
Abstract
Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.
MeSH Record
Classification
Broader headings
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Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
10 entry terms
- Imipemide
- N-Formimidoylthienamycin
- N Formimidoylthienamycin
- Imipenem Anhydrous
- Imipenem, Anhydrous
- MK-0787
- MK0787
- Anhydrous Imipenem
- Anhydrous, Imipenem
- MK 0787
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
89
MeSH Record
Previous Indexing
- Antibiotics (1980-1982)
- Thienamycins (1983-1988)
MeSH Hierarchy
Tree Numbers
MeSH Record
NLM Classification
QV 350
AMA Style
References
- National Library of Medicine. Imipenem. Medical Subject Headings (MeSH). 2026. Unique ID D015378. http://id.nlm.nih.gov/mesh/2026/D015378
- Imipenem. In: Wikidata. https://www.wikidata.org/wiki/Q27122763