Chemicals and Drugs

Terminator Codon

Any codon that signals the termination of genetic translation (TRANSLATION, GENETIC). PEPTIDE TERMINATION FACTORS bind to the stop codon and trigger the hydrolysis of the aminoacyl bond connecting the completed polypeptide to the tRNA. Terminator codons do not specify amino acids.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Any codon that signals the termination of genetic translation (TRANSLATION, GENETIC). PEPTIDE TERMINATION FACTORS bind to the stop codon and trigger the hydrolysis of the aminoacyl bond connecting the completed polypeptide to the tRNA. Terminator codons do not specify amino acids.

MeSH Record

Classification

Broader headings

Narrower headings

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MeSH Record

See Also

MeSH Record

Synonyms

103 entry terms
  • Codon, Stop
  • Codon, Termination
  • Codon, Terminator
  • Stop Codon
  • Stop Signal, Translation
  • Codons, Stop
  • Codons, Termination
  • Codons, Terminator
  • Stop Codons
  • Stop Signals, Translation
  • Termination Codon
  • Termination Codons
  • Terminator Codons
  • Translation Stop Signal
  • Translation Stop Signals
  • Amber Codon
  • Amber Stop Codon
  • Amber Terminator Codon
  • Codon, Amber Stop
  • Codon, Ochre Stop
  • Codon, Opal Stop
  • Ochre Codon
  • Ochre Stop Codon
  • Opal Codon
  • Opal Stop Codon
  • Stop Codon UAA
  • Stop Codon UAG
  • Stop Codon UGA
  • TAA Codon
  • TAG Codon
  • TGA Codon
  • UAA Codon
  • UAA Stop Codon
  • UAG Codon
  • UAG Stop Codon
  • UGA Codon
  • UGA Stop Codon
  • Amber Codons
  • Amber Stop Codons
  • Amber Terminator Codons
  • Codon UAA, Stop
  • Codon UAG, Stop
  • Codon UGA, Stop
  • Codon, Amber
  • Codon, Amber Terminator
  • Codon, Ochre
  • Codon, Opal
  • Codon, TAA
  • Codon, TAG
  • Codon, TGA
  • Codon, UAA
  • Codon, UAA Stop
  • Codon, UAG
  • Codon, UAG Stop
  • Codon, UGA
  • Codon, UGA Stop
  • Codons, Amber
  • Codons, Amber Stop
  • Codons, Amber Terminator
  • Codons, Ochre
  • Codons, Ochre Stop
  • Codons, Opal
  • Codons, Opal Stop
  • Codons, TAA
  • Codons, TAG
  • Codons, TGA
  • Codons, UAA
  • Codons, UAA Stop
  • Codons, UAG
  • Codons, UAG Stop
  • Codons, UGA
  • Codons, UGA Stop
  • Ochre Codons
  • Ochre Stop Codons
  • Opal Codons
  • Opal Stop Codons
  • Stop Codon UGAs
  • Stop Codon, Amber
  • Stop Codon, Ochre
  • Stop Codon, Opal
  • Stop Codon, UAA
  • Stop Codon, UAG
  • Stop Codon, UGA
  • Stop Codons, Amber
  • Stop Codons, Ochre
  • Stop Codons, Opal
  • Stop Codons, UAA
  • Stop Codons, UAG
  • Stop Codons, UGA
  • TAA Codons
  • TAG Codons
  • TGA Codons
  • Terminator Codon, Amber
  • Terminator Codons, Amber
  • UAA Codons
  • UAA Stop Codons
  • UAA, Stop Codon
  • UAG Codons
  • UAG Stop Codons
  • UAG, Stop Codon
  • UGA Codons
  • UGA Stop Codons
  • UGA, Stop Codon

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

95

MeSH Record

Previous Indexing

  • Codon (1975-1994)
  • Genetic Code (1967-1974)

MeSH Hierarchy

Tree Numbers

  1. D13.444w.735w.544w.355w.250w
  2. G05.360w.335w.355w.250w
  3. G05.360w.340w.024.340w.137.190w.250w

AMA Style

References

  1. National Library of Medicine. Terminator Codon. Medical Subject Headings (MeSH). 2026. Unique ID D018388. http://id.nlm.nih.gov/mesh/2026/D018388
  2. Terminator Codon. In: Wikipedia. https://en.wikipedia.org/wiki/Stop_codon
  3. Terminator Codon. In: Wikidata. https://www.wikidata.org/wiki/Q28354