Chemicals and Drugs

TNF-Related Apoptosis-Inducing Ligand Receptors

Tumor necrosis factor receptor family members that are widely expressed and play a role in regulation of peripheral immune responses and APOPTOSIS. The receptors are specific for TNF-RELATED APOPTOSIS-INDUCING LIGAND and signal via conserved DEATH DOMAINS that associate with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Tumor necrosis factor receptor family members that are widely expressed and play a role in regulation of peripheral immune responses and APOPTOSIS. The receptors are specific for TNF-RELATED APOPTOSIS-INDUCING LIGAND and signal via conserved DEATH DOMAINS that associate with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

47 entry terms
  • Receptors, TNF-Related Apoptosis-Inducing Ligand
  • Receptors, TRAIL
  • Receptors, Tumor Necrosis Factor, Member 10
  • TRAIL Receptors
  • Tumor Necrosis Factor Receptor Superfamily, Member 10
  • Receptors, TNF Related Apoptosis Inducing Ligand
  • TNF Related Apoptosis Inducing Ligand Receptors
  • APO2 Receptor
  • CD261 Antigen
  • CD262 Antigen
  • CD264 Antigen
  • DCR2 Receptor
  • DR4 Receptor
  • DR5 Receptor
  • Death Receptor-4
  • Death Receptor-5
  • Decoy Receptor 2, Tumor Necrosis Factor
  • Receptor, TRAIL-1
  • Receptor, TRAIL-2
  • Receptor, TRAIL-4
  • Receptors, Tumor Necrosis Factor, Member 10a
  • Receptors, Tumor Necrosis Factor, Member 10b
  • Receptors, Tumor Necrosis Factor, Member 10d
  • TNF-Related Apoptosis-Inducing Ligand Receptor 2
  • TRAIL Receptor 1
  • TRAIL Receptor 2
  • TRAIL Receptor 4
  • Tumor Necrosis Factor Receptor Superfamily, Member 10a
  • Tumor Necrosis Factor Receptor Superfamily, Member 10b
  • Antigen, CD261
  • Antigen, CD262
  • Antigen, CD264
  • Death Receptor 4
  • Death Receptor 5
  • Receptor 4, TRAIL
  • Receptor, APO2
  • Receptor, DCR2
  • Receptor, DR4
  • Receptor, DR5
  • Receptor, TRAIL 1
  • Receptor, TRAIL 2
  • Receptor, TRAIL 4
  • Receptor-4, Death
  • TNF Related Apoptosis Inducing Ligand Receptor 2
  • TRAIL-1 Receptor
  • TRAIL-2 Receptor
  • TRAIL-4 Receptor

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2007(1997)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.543w.750w.690.600
  2. D12.776w.543w.750w.705w.852w.760w.396

AMA Style

References

  1. National Library of Medicine. TNF-Related Apoptosis-Inducing Ligand Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D053220. http://id.nlm.nih.gov/mesh/2026/D053220
  2. TNF-Related Apoptosis-Inducing Ligand Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q76282264