Chemicals and Drugs

TIE Receptors

A family of structurally-related tyrosine kinase receptors that are expressed predominantly in ENDOTHELIAL CELLS and are essential for development of BLOOD VESSELS (NEOVASCULARIZATION, PHYSIOLOGIC). The name derives from the fact that they are tyrosine kinases that contain Ig and EGF domains.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of structurally-related tyrosine kinase receptors that are expressed predominantly in ENDOTHELIAL CELLS and are essential for development of BLOOD VESSELS (NEOVASCULARIZATION, PHYSIOLOGIC). The name derives from the fact that they are tyrosine kinases that contain Ig and EGF domains.

MeSH Record

Classification

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MeSH Record

Synonyms

9 entry terms
  • Receptor Tyrosine Kinase TIE
  • Receptors, TIE
  • TIE Receptor
  • TIE Receptor Family
  • TIE Receptor Tyrosine Kinase
  • TIE Receptor Tyrosine Kinases
  • Family, TIE Receptor
  • Receptor Family, TIE
  • Receptor, TIE

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

general or unspecified; prefer specifics

MeSH Record

History Note

2004; use RECEPTORS, TIE (NM) 1999-2003

MeSH Record

Previous Indexing

  • Receptor Protein-Tyrosine Kinases (1994-2003)
  • Receptors, Cell Surface (1992-1993)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. TIE Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D042764. http://id.nlm.nih.gov/mesh/2026/D042764
  2. TIE Receptors. In: Wikipedia. https://en.wikipedia.org/wiki/Angiopoietin_receptor
  3. TIE Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q4763284