Structured Summary
Abstract
A TIE receptor tyrosine kinase that is found almost exclusively on ENDOTHELIAL CELLS. It is required for both normal embryonic vascular development (NEOVASCULARIZATION, PHYSIOLOGIC) and tumor angiogenesis (NEOVASCULARIZATION, PATHOLOGIC).
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
15 entry terms
- Angiopoietin Receptor Tie-2
- Receptor, TIE-2
- TIE-2 Receptor Tyrosine Kinase
- TIE-2-RTK
- TIE2 Tyrosine Kinase
- Tek Receptor
- Tie2 Receptor
- Angiopoietin Receptor Tie 2
- Receptor Tie-2, Angiopoietin
- Receptor, TIE 2
- Receptor, Tek
- Receptor, Tie2
- TIE 2 Receptor Tyrosine Kinase
- Tie-2, Angiopoietin Receptor
- Tyrosine Kinase, TIE2
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
see SCR for organism-specific terms
MeSH Record
History Note
2004; use RECEPTOR TIE-2 (NM) 1993-2003
MeSH Record
Previous Indexing
- Protein-Tyrosine Kinase (1993)
- Receptor Protein-Tyrosine Kinases (1994-2003)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. TIE-2 Receptor. Medical Subject Headings (MeSH). 2026. Unique ID D042787. http://id.nlm.nih.gov/mesh/2026/D042787
- TIE-2 Receptor. In: Wikidata. https://www.wikidata.org/wiki/Q21097266