Chemicals and Drugs

T-bet Transcription Factor

A transcription factor of the T-box family of transcription factors, functions in immune system regulation, particularly in T-cell differentiation. It also is involved in the development of Th1 cells and the regulation of CXCR3 expression.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A transcription factor of the T-box family of transcription factors, functions in immune system regulation, particularly in T-cell differentiation. It also is involved in the development of Th1 cells and the regulation of CXCR3 expression.

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Classification

Broader headings

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MeSH Record

Synonyms

12 entry terms
  • T-box Transcription Factor
  • T-box Transcription Factor TBX21
  • Transcription Factor TBLYM
  • Factor TBLYM, Transcription
  • Factor, T-bet Transcription
  • Factor, T-box Transcription
  • T bet Transcription Factor
  • T box Transcription Factor
  • T box Transcription Factor TBX21
  • TBLYM, Transcription Factor
  • Transcription Factor, T-bet
  • Transcription Factor, T-box

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2025 (2000)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. T-bet Transcription Factor. Medical Subject Headings (MeSH). 2026. Unique ID D000098815. http://id.nlm.nih.gov/mesh/2026/D000098815
  2. T-bet Transcription Factor. In: Wikidata. https://www.wikidata.org/wiki/Q21127364