Chemicals and Drugs

T-Box Domain Proteins

Proteins containing a region of conserved sequence, about 200 amino acids long, which encodes a particular sequence specific DNA binding domain (the T-box domain). These proteins are transcription factors that control developmental pathways. The prototype of this family is the mouse Brachyury (or T) gene product.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Proteins containing a region of conserved sequence, about 200 amino acids long, which encodes a particular sequence specific DNA binding domain (the T-box domain). These proteins are transcription factors that control developmental pathways. The prototype of this family is the mouse Brachyury (or T) gene product.

MeSH Record

Classification

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MeSH Record

Synonyms

2 entry terms
  • Proteins, T-Box Domain
  • T Box Domain Proteins

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2000

MeSH Record

Previous Indexing

  • DNA-Binding Proteins (1996-1999)
  • Transcription Factors (1996-1999)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. T-Box Domain Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D020825. http://id.nlm.nih.gov/mesh/2026/D020825
  2. T-Box Domain Proteins. In: Wikipedia. https://en.wikipedia.org/wiki/T-box
  3. T-Box Domain Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q7667886