Chemicals and Drugs

Syndecans

A family of transmembrane glycoproteins that contain a short cytoplasmic domain, a single-span transmembrane domain, and an extracellular domain with heparin sulfate and CHONDROITIN SULFATE chains. Syndecans interact with a variety of heparin-binding INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS and may play a role in modulating cellular signaling during EMBRYONIC DEVELOPMENT, tumorigenesis, and angiogenesis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of transmembrane glycoproteins that contain a short cytoplasmic domain, a single-span transmembrane domain, and an extracellular domain with heparin sulfate and CHONDROITIN SULFATE chains. Syndecans interact with a variety of heparin-binding INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS and may play a role in modulating cellular signaling during EMBRYONIC DEVELOPMENT, tumorigenesis, and angiogenesis.

MeSH Record

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MeSH Record

Synonyms

1 entry terms
  • Syndecan

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2007(1989)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.890w.847w
  2. D09w.400w.430w.930w.350.500w
  3. D12.776w.395w.550w.847w
  4. D12.776w.395w.650w.350.500w
  5. D12.776w.543w.550w.847w

AMA Style

References

  1. National Library of Medicine. Syndecans. Medical Subject Headings (MeSH). 2026. Unique ID D053667. http://id.nlm.nih.gov/mesh/2026/D053667
  2. Syndecans. In: Wikipedia. https://en.wikipedia.org/wiki/Syndecan
  3. Syndecans. In: Wikidata. https://www.wikidata.org/wiki/Q24719732