Chemicals and Drugs

Heparan Sulfate Proteoglycans

Ubiquitous macromolecules associated with the cell surface and extracellular matrix of a wide range of cells of vertebrate and invertebrate tissues. They are essential cofactors in cell-matrix adhesion processes, in cell-cell recognition systems, and in receptor-growth factor interactions. (From Cancer Metastasis Rev 1996; 15(2): 177-86; Hepatology 1996; 24(3): 524-32)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Ubiquitous macromolecules associated with the cell surface and extracellular matrix of a wide range of cells of vertebrate and invertebrate tissues. They are essential cofactors in cell-matrix adhesion processes, in cell-cell recognition systems, and in receptor-growth factor interactions. (From Cancer Metastasis Rev 1996; 15(2): 177-86; Hepatology 1996; 24(3): 524-32)

MeSH Record

Classification

Narrower headings

Related Concepts

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MeSH Record

Synonyms

6 entry terms
  • HSPG
  • Heparan Sulfate Proteoglycan
  • Proteoheparan Sulfate
  • Proteoglycan, Heparan Sulfate
  • Proteoglycans, Heparan Sulfate
  • Sulfate Proteoglycans, Heparan

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

do not confuse with HEPARAN SULFATE see Heparan Sulfate

MeSH Record

History Note

2006(1982)

MeSH Record

Previous Indexing

  • Heparitin Sulfate (1982-1997)
  • Proteochondroitin Sulfates (1982-1992)
  • Proteoglycans (1982-1997)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Heparan Sulfate Proteoglycans. Medical Subject Headings (MeSH). 2026. Unique ID D019812. http://id.nlm.nih.gov/mesh/2026/D019812
  2. Heparan Sulfate Proteoglycans. In: Wikidata. https://www.wikidata.org/wiki/Q66589633