Structured Summary
Abstract
An SH2 domain-containing non-receptor tyrosine kinase that regulates signal transduction downstream of a variety of receptors including B-CELL ANTIGEN RECEPTORS. It functions in both INNATE IMMUNITY and ADAPTIVE IMMUNITY and also mediates signaling in CELL ADHESION; OSTEOGENESIS; PLATELET ACTIVATION; and vascular development.
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Synonyms
7 entry terms
- SYK Tyrosine Kinase
- Spleen Tyrosine Kinase
- Kinase, SYK Tyrosine
- Kinase, Spleen Tyrosine
- Kinase, Syk
- Tyrosine Kinase, SYK
- Tyrosine Kinase, Spleen
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017 (1992)
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AMA Style
References
- National Library of Medicine. Syk Kinase. Medical Subject Headings (MeSH). 2026. Unique ID D000072377. http://id.nlm.nih.gov/mesh/2026/D000072377
- Syk Kinase. In: Wikipedia. https://en.wikipedia.org/wiki/Tyrosine-protein_kinase_SYK
- Syk Kinase. In: Wikidata. https://www.wikidata.org/wiki/Q7660502