Chemicals and Drugs

Surrogate Immunoglobulin Light Chains

An immunolglobulin light chain-like protein composed of an IMMUNOGLOBULIN VARIABLE REGION-like peptide (such as light chain like lambda5 peptide) and an IMMUNOGLOBULIN CONSTANT REGION-like peptide (such as Vpreb1 peptide). Surrogate light chains associate with MU IMMUNOGLOBULIN HEAVY CHAINS in place of a conventional immunoglobulin light chains to form pre-B cell receptors.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An immunolglobulin light chain-like protein composed of an IMMUNOGLOBULIN VARIABLE REGION-like peptide (such as light chain like lambda5 peptide) and an IMMUNOGLOBULIN CONSTANT REGION-like peptide (such as Vpreb1 peptide). Surrogate light chains associate with MU IMMUNOGLOBULIN HEAVY CHAINS in place of a conventional immunoglobulin light chains to form pre-B cell receptors.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

21 entry terms
  • Immunoglobulin Light Chains, Surrogate
  • Pseudo Immunoglobulin Light Chain
  • Surrogate L Chain Protein
  • Surrogate Light Chain
  • Surrogate Light Chains
  • psiL Chain, Immunoglobulin
  • Immunoglobulin psiL Chain
  • Light Chain, Surrogate
  • Light Chains, Surrogate
  • Immunoglobulin Light Chain-Like lambda5 Peptide
  • Surrogate Immunoglobulin kappa Light Chain
  • Surrogate kappa Light Chain
  • Surrogate lambda Light Chain
  • VpreB-lambda 5 SL Chain
  • VpreB-lambda5 Surrogate Light Chain
  • lambda5 Peptide, Immunoglobulin Light Chain-Like
  • psi lambda Light Chain
  • Immunoglobulin Light Chain Like lambda5 Peptide
  • VpreB lambda 5 SL Chain
  • VpreB lambda5 Surrogate Light Chain
  • lambda5 Peptide, Immunoglobulin Light Chain Like

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2008

MeSH Record

Previous Indexing

  • Immunoglobulin Light Chains (1991-2007)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.124w.486.485.705.750w.775
  2. D12.776w.124w.790.651.705.750w.775
  3. D12.776w.124w.790.651.950w.750.500
  4. D12.776w.377w.715.548.705.750w.775
  5. D12.776w.377w.715.548.950w.750.500
  6. D12.776w.543w.750w.705w.816.821w.750.500

AMA Style

References

  1. National Library of Medicine. Surrogate Immunoglobulin Light Chains. Medical Subject Headings (MeSH). 2026. Unique ID D054444. http://id.nlm.nih.gov/mesh/2026/D054444
  2. Surrogate Immunoglobulin Light Chains. In: Wikidata. https://www.wikidata.org/wiki/Q77201338