Chemicals and Drugs

Sulfamethoxazole

A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)

Chemical Identity

Chemical Information

Molecular Formula
C10H11N3O3S
Molecular Weight
253.28 g/mol
CAS Registry No.
723-46-6
IUPAC Name
4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide
InChIKey
JLKIGFTWXXRPMT-UHFFFAOYSA-N
SMILES
CC1=CC(=NO1)NS(=O)(=O)C2=CC=C(C=C2)N
MeSH Unique ID
D013420
Source
PubChem CID 5329

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

4 entry terms
  • Sulfamethylisoxazole
  • Sulfisomezole
  • Sulphamethoxazole
  • Gantanol

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

a sulfanilamide anti-infective

MeSH Record

History Note

68(63)

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.884w.060.300w
  2. D02w.065w.884w.725.867w
  3. D02w.092w.146.807.867w
  4. D02w.455w.426w.559w.389.085.300w
  5. D02w.886w.590w.700w.090.300w
  6. D02w.886w.590w.700w.725.867w

MeSH Record

NLM Classification

QV 265

AMA Style

References

  1. National Library of Medicine. Sulfamethoxazole. Medical Subject Headings (MeSH). 2026. Unique ID D013420. http://id.nlm.nih.gov/mesh/2026/D013420
  2. Sulfamethoxazole. In: Wikipedia. https://en.wikipedia.org/wiki/Sulfamethoxazole
  3. Sulfamethoxazole. In: Wikidata. https://www.wikidata.org/wiki/Q415843
  4. Sulfamethoxazole. In: PubChem Compound. CID 5329. https://pubchem.ncbi.nlm.nih.gov/compound/5329