Chemicals and Drugs

Stromal Interaction Molecules

Membrane-associated calcium-binding proteins that are characterized by N-terminal EF HAND MOTIFS and a STERILE ALPHA MOTIF. They function as sensors of ENDOPLASMIC RETICULUM calcium levels and translocate from the ER to the plasma membrane to activate CALCIUM CHANNELS in response to intracellular calcium depletion.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Membrane-associated calcium-binding proteins that are characterized by N-terminal EF HAND MOTIFS and a STERILE ALPHA MOTIF. They function as sensors of ENDOPLASMIC RETICULUM calcium levels and translocate from the ER to the plasma membrane to activate CALCIUM CHANNELS in response to intracellular calcium depletion.

MeSH Record

Classification

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MeSH Record

Synonyms

3 entry terms
  • Stromal Interaction Molecule
  • Interaction Molecule, Stromal
  • Molecule, Stromal Interaction

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017

MeSH Record

Previous Indexing

  • Calcium Channels (1996-2016)
  • Membrane Proteins (1997-2016)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Stromal Interaction Molecules. Medical Subject Headings (MeSH). 2026. Unique ID D000071736. http://id.nlm.nih.gov/mesh/2026/D000071736
  2. Stromal Interaction Molecules. In: Wikidata. https://www.wikidata.org/wiki/Q54443832