Chemicals and Drugs

Stromal Interaction Molecule 1

A stromal interaction molecule that functions in the regulation of calcium influx following depletion of intracellular calcium in the ENDOPLASMIC RETICULUM. It translocates to the plasma membrane upon calcium depletion where it activates the CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL ORAI1.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A stromal interaction molecule that functions in the regulation of calcium influx following depletion of intracellular calcium in the ENDOPLASMIC RETICULUM. It translocates to the plasma membrane upon calcium depletion where it activates the CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL ORAI1.

MeSH Record

Classification

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MeSH Record

Synonyms

1 entry terms
  • STIM1 Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017

MeSH Record

Previous Indexing

  • Calcium Channels (1996-2016)
  • Membrane Proteins (1997-2016)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Stromal Interaction Molecule 1. Medical Subject Headings (MeSH). 2026. Unique ID D000071737. http://id.nlm.nih.gov/mesh/2026/D000071737
  2. Stromal Interaction Molecule 1. In: Wikidata. https://www.wikidata.org/wiki/Q24785770