Chemicals and Drugs

Streptodornase and Streptokinase

A mixture of the enzymes (streptokinase and streptodornase) produced by hemolytic streptococci. It is used topically on surface lesions and by instillation in closed body cavities to remove clotted blood or fibrinous or purulent accumulations. It is also used as a skin test antigen in evaluating generalized cell-mediated immunodeficiency. (Dorland, 27th ed) EC 3.-.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A mixture of the enzymes (streptokinase and streptodornase) produced by hemolytic streptococci. It is used topically on surface lesions and by instillation in closed body cavities to remove clotted blood or fibrinous or purulent accumulations. It is also used as a skin test antigen in evaluating generalized cell-mediated immunodeficiency. (Dorland, 27th ed) EC 3.-.

MeSH Record

Classification

Broader headings

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MeSH Record

See Also

MeSH Record

Synonyms

2 entry terms
  • Streptokinase and Streptodornase
  • Varidase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

a pharm prep as ther agent combining both enzymes in a single dosage form; do not confuse with STREPTODORNASE see DEOXYRIBONUCLEASE I nor with STREPTOKINASE

MeSH Record

History Note

FIBRINOKINASE & PLASMINOKINASE were see STREPTODORNASE AND STREPTOKINASE 1963-93

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.352w.335w.350w.250.900
  2. D08.811w.277w.656w.300w.775.900
  3. D12.776w.124w.125.662w.537.900

AMA Style

References

  1. National Library of Medicine. Streptodornase and Streptokinase. Medical Subject Headings (MeSH). 2026. Unique ID D013299. http://id.nlm.nih.gov/mesh/2026/D013299
  2. Streptodornase and Streptokinase. In: Wikidata. https://www.wikidata.org/wiki/Q77927738