Chemicals and Drugs

Steroidogenic Factor 1

A transcription factor and member of the nuclear receptor family NR5 that is expressed throughout the adrenal and reproductive axes during development. It plays an important role in sexual differentiation, formation of primary steroidogenic tissues, and their functions in post-natal and adult life. It regulates the expression of key steroidogenic enzymes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A transcription factor and member of the nuclear receptor family NR5 that is expressed throughout the adrenal and reproductive axes during development. It plays an important role in sexual differentiation, formation of primary steroidogenic tissues, and their functions in post-natal and adult life. It regulates the expression of key steroidogenic enzymes.

MeSH Record

Classification

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

11 entry terms
  • AD4BP Protein
  • Ad4-Binding Protein
  • Adrenal 4 Binding Protein
  • FTZF1 Protein
  • Fushi Tarazu Factor Homolog 1
  • NR5A1 Protein
  • Nuclear Receptor 5A1 Protein
  • SF-1 Transcription Factor
  • Steroid Hormone Receptor Ad4BP
  • Ad4 Binding Protein
  • Transcription Factor, SF-1

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2008

MeSH Record

Previous Indexing

  • Homeodomain Proteins (1993-2007)
  • Receptors, Cytoplasmic and Nuclear (1993-2007)
  • Transcription Factors (1993-2007)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Steroidogenic Factor 1. Medical Subject Headings (MeSH). 2026. Unique ID D054339. http://id.nlm.nih.gov/mesh/2026/D054339
  2. Steroidogenic Factor 1. In: Wikidata. https://www.wikidata.org/wiki/Q7611614