Structured Summary
Abstract
A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Chemical Identity
Chemical Information
- Molecular Formula
- C10H12N2O4
- Molecular Weight
- 224.21 g/mol
- CAS Registry No.
- 3056-17-5
- IUPAC Name
- 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione
- InChIKey
- XNKLLVCARDGLGL-JGVFFNPUSA-N
- SMILES
- CC1=CN(C(=O)NC1=O)[C@H]2C=C[C@H](O2)CO
- MeSH Unique ID
- D018119
- Source
- PubChem CID 18283
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
9 entry terms
- 2',3'-Didehydro-2',3'-dideoxythmidine
- 2',3'-Didehydro-3'-deoxythymidine
- D4T
- 2',3' Didehydro 3' deoxythymidine
- BMY-27857
- Stavudine, Monosodium Salt
- Zerit
- BMY 27857
- BMY27857
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
1994; use STAVUDINE 1987-93
MeSH Record
Previous Indexing
- Dideoxynucleosides (1989-1993)
- Thymidine/analogs & derivatives (1987-1988)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Stavudine. Medical Subject Headings (MeSH). 2026. Unique ID D018119. http://id.nlm.nih.gov/mesh/2026/D018119
- Stavudine. In: Wikipedia. https://en.wikipedia.org/wiki/Stavudine
- Stavudine. In: Wikidata. https://www.wikidata.org/wiki/Q423984
- Stavudine. In: PubChem Compound. CID 18283. https://pubchem.ncbi.nlm.nih.gov/compound/18283