Chemicals and Drugs

Spermine

A biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria. It is found as a polycation at all pH values. Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria. It is found as a polycation at all pH values. Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure.

Chemical Identity

Chemical Information

Molecular Formula
C10H26N4
Molecular Weight
202.34 g/mol
CAS Registry No.
71-44-3
IUPAC Name
N,N'-bis(3-aminopropyl)butane-1,4-diamine
InChIKey
PFNFFQXMRSDOHW-UHFFFAOYSA-N
SMILES
C(CCNCCCN)CNCCCN
MeSH Unique ID
D013096
Source
PubChem CID 1103

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Aspects Covered

27 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Numbers

  1. D02w.092w.211w.415.701w.801w.821w
  2. D02w.092w.782w.802w

AMA Style

References

  1. National Library of Medicine. Spermine. Medical Subject Headings (MeSH). 2026. Unique ID D013096. http://id.nlm.nih.gov/mesh/2026/D013096
  2. Spermine. In: Wikipedia. https://en.wikipedia.org/wiki/Spermine
  3. Spermine. In: Wikidata. https://www.wikidata.org/wiki/Q424597
  4. Spermine. In: PubChem Compound. CID 1103. https://pubchem.ncbi.nlm.nih.gov/compound/1103