Chemicals and Drugs

Spermidine

A polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.

Chemical Identity

Chemical Information

Molecular Formula
C7H19N3
Molecular Weight
145.25 g/mol
CAS Registry No.
124-20-9
IUPAC Name
N'-(3-aminopropyl)butane-1,4-diamine
InChIKey
ATHGHQPFGPMSJY-UHFFFAOYSA-N
SMILES
C(CCNCCCN)CN
MeSH Unique ID
D013095
Source
PubChem CID 1102

MeSH Record

Classification

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MeSH Record

Aspects Covered

27 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

73(71)

MeSH Record

Previous Indexing

  • Amines (1966-1970)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Spermidine. Medical Subject Headings (MeSH). 2026. Unique ID D013095. http://id.nlm.nih.gov/mesh/2026/D013095
  2. Spermidine. In: Wikipedia. https://en.wikipedia.org/wiki/Spermidine
  3. Spermidine. In: Wikidata. https://www.wikidata.org/wiki/Q418834
  4. Spermidine. In: PubChem Compound. CID 1102. https://pubchem.ncbi.nlm.nih.gov/compound/1102