Chemicals and Drugs

Sirtuin 3

A sirtuin family member found primarily in MITOCHONDRIA. It is a multifunctional enzyme that contains a NAD-dependent deacetylase activity that is specific for HISTONES and a mono-ADP-ribosyltransferase activity.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A sirtuin family member found primarily in MITOCHONDRIA. It is a multifunctional enzyme that contains a NAD-dependent deacetylase activity that is specific for HISTONES and a mono-ADP-ribosyltransferase activity.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

2 entry terms
  • Silent Mating Type Information Regulation 2 Homolog 3
  • Sirt3

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2010

MeSH Record

Previous Indexing

  • Histone Deacetylases (2002-2005)
  • Mitochondrial Proteins (2006-2009)
  • Sirtuins (2006-2009)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.087w.520w.200.650.600
  2. D08.811w.913w.400w.725w.115.961.600
  3. D12.776w.476.900.600
  4. D12.776w.575.875

AMA Style

References

  1. National Library of Medicine. Sirtuin 3. Medical Subject Headings (MeSH). 2026. Unique ID D056566. http://id.nlm.nih.gov/mesh/2026/D056566
  2. Sirtuin 3. In: Wikidata. https://www.wikidata.org/wiki/Q21116855