Chemicals and Drugs

Signaling Lymphocytic Activation Molecule Family Member 1

A 70-kDa SLAM family receptor that consists of an extracellular IMMUNOGLOBULIN-LIKE DOMAIN and an IMMUNOGLOBULIN C2-SET DOMAIN. It is expressed primarily by THYMOCYTES and activated T-LYMPHOCYTES, as well as by MACROPHAGES and DENDRITIC CELLS. It binds SLAMF1 receptors on other cells to mediate T-cell maturation and proliferation. It is also a receptor for the MEASLES VIRUS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A 70-kDa SLAM family receptor that consists of an extracellular IMMUNOGLOBULIN-LIKE DOMAIN and an IMMUNOGLOBULIN C2-SET DOMAIN. It is expressed primarily by THYMOCYTES and activated T-LYMPHOCYTES, as well as by MACROPHAGES and DENDRITIC CELLS. It binds SLAMF1 receptors on other cells to mediate T-cell maturation and proliferation. It is also a receptor for the MEASLES VIRUS.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

7 entry terms
  • CD150 Antigen
  • CDw150 Protein
  • SLAM Protein
  • SLAM Receptor
  • SLAMF1 Protein
  • SLAMF1 Receptor
  • Antigen, CD150

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2017 (1995)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.890w.736w.500
  2. D12.776w.395w.550w.736w.500
  3. D12.776w.543w.550w.746w.500
  4. D12.776w.543w.750w.705w.970w.500

AMA Style

References

  1. National Library of Medicine. Signaling Lymphocytic Activation Molecule Family Member 1. Medical Subject Headings (MeSH). 2026. Unique ID D000071177. http://id.nlm.nih.gov/mesh/2026/D000071177
  2. Signaling Lymphocytic Activation Molecule Family Member 1. In: Wikidata. https://www.wikidata.org/wiki/Q22678676