Chemicals and Drugs

Sertraline

A selective serotonin uptake inhibitor that is used in the treatment of depression.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A selective serotonin uptake inhibitor that is used in the treatment of depression.

Chemical Identity

Chemical Information

Molecular Formula
C17H17Cl2N
Molecular Weight
306.2 g/mol
CAS Registry No.
79617-96-2
IUPAC Name
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
InChIKey
VGKDLMBJGBXTGI-SJCJKPOMSA-N
SMILES
CN[C@H]1CC[C@H](C2=CC=CC=C12)C3=CC(=C(C=C3)Cl)Cl
MeSH Unique ID
D020280
Source
PubChem CID 68617

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

20 entry terms
  • Altruline
  • Apo-Sertraline
  • Aremis
  • Besitran
  • Gen-Sertraline
  • Gladem
  • Lustral
  • Novo-Sertraline
  • Rhoxal-sertraline
  • Sealdin
  • Sertraline Hydrochloride
  • Sertraline Hydrochloride (1S-cis)-Isomer
  • Zoloft
  • ratio-Sertraline
  • Apo Sertraline
  • Gen Sertraline
  • Hydrochloride, Sertraline
  • Novo Sertraline
  • Rhoxal sertraline
  • ratio Sertraline

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

99; use SERTRALINE (NM) 1983-98

MeSH Record

Previous Indexing

  • 1-Naphthylamine/analogs & derivatives (1983-1998)

MeSH Hierarchy

Tree Numbers

  1. D02w.092w.705w.800w
  2. D02w.455w.426w.559w.847w.638.845w.800w
  3. D04w.615w.638.845w.800w

AMA Style

References

  1. National Library of Medicine. Sertraline. Medical Subject Headings (MeSH). 2026. Unique ID D020280. http://id.nlm.nih.gov/mesh/2026/D020280
  2. Sertraline. In: Wikipedia. https://en.wikipedia.org/wiki/Sertraline
  3. Sertraline. In: Wikidata. https://www.wikidata.org/wiki/Q407617
  4. Sertraline. In: PubChem Compound. CID 68617. https://pubchem.ncbi.nlm.nih.gov/compound/68617