Structured Summary
Abstract
A signal transducer and activator of transcription that mediates cellular responses to a variety of CYTOKINES. Stat5 activation is associated with transcription of CELL CYCLE regulators such as CYCLIN KINASE INHIBITOR P21 and anti-apoptotic genes such as BCL-2 GENES. Stat5 is constitutively activated in many patients with acute MYELOID LEUKEMIA.
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Classification
Broader headings
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Synonyms
17 entry terms
- STAT5 Protein
- Signal Transducer and Activator of Transcription 5
- Factor, STAT5 Transcription
- Transcription Factor, STAT5
- Mammary Gland Factor
- Mammary Gland-Specific Nuclear Factor
- STAT5a Protein
- STAT5a Transcription Factor
- STAT5alpha Protein
- STAT5b Protein
- STAT5b Transcription Factor
- STAT5beta Protein
- Signal Transducer and Activator of Transcription 5A
- Signal Transducer and Activator of Transcription 5B
- Mammary Gland Specific Nuclear Factor
- Transcription Factor, STAT5a
- Transcription Factor, STAT5b
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006(1992)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. STAT5 Transcription Factor. Medical Subject Headings (MeSH). 2026. Unique ID D050799. http://id.nlm.nih.gov/mesh/2026/D050799
- STAT5 Transcription Factor. In: Wikipedia. https://en.wikipedia.org/wiki/STAT5
- STAT5 Transcription Factor. In: Wikidata. https://www.wikidata.org/wiki/Q4210018