Chemicals and Drugs

Ribonuclease P

An RNA-containing enzyme that plays an essential role in tRNA processing by catalyzing the endonucleolytic cleavage of TRANSFER RNA precursors. It removes the extra 5'-nucleotides from tRNA precursors to generate mature tRNA molecules.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An RNA-containing enzyme that plays an essential role in tRNA processing by catalyzing the endonucleolytic cleavage of TRANSFER RNA precursors. It removes the extra 5'-nucleotides from tRNA precursors to generate mature tRNA molecules.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

3 entry terms
  • RNase P
  • RNA Catalytic Subunit, Ribonuclease P
  • Ribonuclease P, RNA Catalytic Subunit

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2004; use RIBONUCLEASE P (NM) 1980-2003

MeSH Record

Previous Indexing

  • Endonucleases (1979-2003)
  • Endoribonucleases (1983-2003)
  • RNA, Catalytic (1991-2003)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.352w.700w.350w.711w
  2. D08.811w.797.500w
  3. D12.776w.157w.725w.500w.625w
  4. D12.776w.664w.962w.500w.625w

AMA Style

References

  1. National Library of Medicine. Ribonuclease P. Medical Subject Headings (MeSH). 2026. Unique ID D043262. http://id.nlm.nih.gov/mesh/2026/D043262
  2. Ribonuclease P. In: Wikipedia. https://en.wikipedia.org/wiki/Ribonuclease_P
  3. Ribonuclease P. In: Wikidata. https://www.wikidata.org/wiki/Q76826611