Chemicals and Drugs

Catalytic RNA

RNA that has catalytic activity. The catalytic RNA sequence folds to form a complex surface that can function as an enzyme in reactions with itself and other molecules. It may function even in the absence of protein. There are numerous examples of RNA species that are acted upon by catalytic RNA, however the scope of this enzyme class is not limited to a particular type of substrate.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

RNA that has catalytic activity. The catalytic RNA sequence folds to form a complex surface that can function as an enzyme in reactions with itself and other molecules. It may function even in the absence of protein. There are numerous examples of RNA species that are acted upon by catalytic RNA, however the scope of this enzyme class is not limited to a particular type of substrate.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

3 entry terms
  • RNA, Catalytic
  • Ribozyme
  • Ribozymes

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

91

MeSH Record

Previous Indexing

  • RNA Splicing (1986-1990)
  • RNA, Ribosomal (1986-1990)

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

QU 58.7

AMA Style

References

  1. National Library of Medicine. Catalytic RNA. Medical Subject Headings (MeSH). 2026. Unique ID D016337. http://id.nlm.nih.gov/mesh/2026/D016337
  2. Catalytic RNA. In: Wikidata. https://www.wikidata.org/wiki/Q76699642