Chemicals and Drugs

RANK Ligand

A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B and OSTEOPROTEGERIN. It plays an important role in regulating OSTEOCLAST differentiation and activation.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B and OSTEOPROTEGERIN. It plays an important role in regulating OSTEOCLAST differentiation and activation.

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Synonyms

16 entry terms
  • CD254 Antigen
  • OPGL Protein
  • Osteoclast Differentiation Factor
  • Osteoprotegerin Ligand
  • RANKL Protein
  • Receptor Activator of Nuclear Factor-kappa B Ligand
  • Receptor Activator of Nuclear Factor-kappaB Ligand
  • TNF Superfamily, Member 11
  • TRANCE Protein
  • Tumor Necrosis Factor Ligand Superfamily Member 11
  • Tumor Necrosis Factor-Related Activation-Induced Cytokine
  • Antigen, CD254
  • Differentiation Factor, Osteoclast
  • Receptor Activator of Nuclear Factor kappa B Ligand
  • Receptor Activator of Nuclear Factor kappaB Ligand
  • Tumor Necrosis Factor Related Activation Induced Cytokine

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007(1997)

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AMA Style

References

  1. National Library of Medicine. RANK Ligand. Medical Subject Headings (MeSH). 2026. Unique ID D053245. http://id.nlm.nih.gov/mesh/2026/D053245
  2. RANK Ligand. In: Wikipedia. https://en.wikipedia.org/wiki/RANKL
  3. RANK Ligand. In: Wikidata. https://www.wikidata.org/wiki/Q418934