Chemicals and Drugs

Quinestrol

The 3-cyclopentyl ether of ETHINYL ESTRADIOL. After gastrointestinal absorption, it is stored in ADIPOSE TISSUE, slowly released, and metabolized principally to the parent compound. It has been used in ESTROGEN REPLACEMENT THERAPY. (From AMA Drug Evaluations Annual, 1992, p1011)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The 3-cyclopentyl ether of ETHINYL ESTRADIOL. After gastrointestinal absorption, it is stored in ADIPOSE TISSUE, slowly released, and metabolized principally to the parent compound. It has been used in ESTROGEN REPLACEMENT THERAPY. (From AMA Drug Evaluations Annual, 1992, p1011)

Chemical Identity

Chemical Information

Molecular Formula
C25H32O2
Molecular Weight
364.5 g/mol
CAS Registry No.
152-43-2
IUPAC Name
(8R,9S,13S,14S,17R)-3-cyclopentyloxy-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol
InChIKey
PWZUUYSISTUNDW-VAFBSOEGSA-N
SMILES
C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=C3C=CC(=C4)OC5CCCC5
MeSH Unique ID
D011800
Source
PubChem CID 9046

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

3 entry terms
  • Ethinyl Estradiol 3-Cyclopentyl Ether
  • Ethinyl Estradiol 3 Cyclopentyl Ether
  • Estrovis

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(72); was see under NORPREGNATRIENES 1972-90

MeSH Record

Previous Indexing

  • Contraceptives, Oral (1966-1971)
  • Estrogens (1966-1971)

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.668w.651.568.291w.750w
  2. D06.472w.334.851w.437.968.500w.750w

AMA Style

References

  1. National Library of Medicine. Quinestrol. Medical Subject Headings (MeSH). 2026. Unique ID D011800. http://id.nlm.nih.gov/mesh/2026/D011800
  2. Quinestrol. In: Wikipedia. https://en.wikipedia.org/wiki/Quinestrol
  3. Quinestrol. In: Wikidata. https://www.wikidata.org/wiki/Q3927871
  4. Quinestrol. In: PubChem Compound. CID 9046. https://pubchem.ncbi.nlm.nih.gov/compound/9046