Structured Summary
Abstract
PUROMYCIN derivative that lacks the methoxyphenylalanyl group on the amine of the sugar ring. It is an antibiotic with antineoplastic properties and can cause nephrosis.
Chemical Identity
Chemical Information
- Molecular Formula
- C12H18N6O3
- Molecular Weight
- 294.31 g/mol
- CAS Registry No.
- 58-60-6
- IUPAC Name
- (2R,3R,4S,5S)-4-amino-2-[6-(dimethylamino)purin-9-yl]-5-(hydroxymethyl)oxolan-3-ol
- InChIKey
- RYSMHWILUNYBFW-GRIPGOBMSA-N
- SMILES
- CN(C)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)N)O
- MeSH Unique ID
- D011692
- Source
- PubChem CID 6020
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
4 entry terms
- 3'-Amino-3'-deoxy-N,N-dimethyladenosine
- 3' Amino 3' deoxy N,N dimethyladenosine
- Aminonucleoside, Puromycin
- Aminonucleoside
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
91(75); was see under PUROMYCIN 1975-90
MeSH Record
Previous Indexing
- Amino Sugars (1974)
- Antibiotics, Antineoplastic (1972-1974)
- Deoxyadenosine (1972-1974)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Puromycin Aminonucleoside. Medical Subject Headings (MeSH). 2026. Unique ID D011692. http://id.nlm.nih.gov/mesh/2026/D011692
- Puromycin Aminonucleoside. In: Wikidata. https://www.wikidata.org/wiki/Q27120494
- Puromycin Aminonucleoside. In: PubChem Compound. CID 6020. https://pubchem.ncbi.nlm.nih.gov/compound/6020