Structured Summary
Abstract
A cinnamamido ADENOSINE found in STREPTOMYCES alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.
Chemical Identity
Chemical Information
- Molecular Formula
- C22H29N7O5
- Molecular Weight
- 471.5 g/mol
- CAS Registry No.
- 53-79-2
- IUPAC Name
- (2S)-2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide
- InChIKey
- RXWNCPJZOCPEPQ-NVWDDTSBSA-N
- SMILES
- CN(C)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)NC(=O)[C@H](CC4=CC=C(C=C4)OC)N)O
- MeSH Unique ID
- D011691
- Source
- PubChem CID 439530
MeSH Record
Classification
Broader headings
Narrower headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
9 entry terms
- CL-13900
- P-638
- Puromycin Dihydrochloride
- Puromycin Hydrochloride
- Stylomycin
- CL 13900
- CL13900
- P 638
- P638
MeSH Record
Aspects Covered
26 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
65(63)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Puromycin. Medical Subject Headings (MeSH). 2026. Unique ID D011691. http://id.nlm.nih.gov/mesh/2026/D011691
- Puromycin. In: Wikipedia. https://en.wikipedia.org/wiki/Puromycin
- Puromycin. In: Wikidata. https://www.wikidata.org/wiki/Q424696
- Puromycin. In: PubChem Compound. CID 439530. https://pubchem.ncbi.nlm.nih.gov/compound/439530